Stem Cell Therapy
How do stem cells work?
Basic, unspecialized cells called stem cells exist in the human body and have a remarkable capacity to regenerate. They distinguish and grow into the desired tissue or organ, assisting in the treatment of a wide range of deadly and non-fatal illnesses include cancer, Parkinson’s disease, spinal cord injuries, multiple sclerosis, and muscle injury.
Studying stem cells can help us better understand how they develop into the dazzling variety of specialized cells that make us who we are. Stem cells have the potential to advance numerous fields of health and medical research. Birth abnormalities and cancer are two of the most severe medical diseases that can be brought on by issues that arise throughout this procedure. Understanding how cells develop normally will help us comprehend and possibly rectify the mistakes that result in various medical problems.
Diseases and Stem Cells
We can better grasp how stem cells develop into the dazzling variety of specialized cells that make us who we are by studying how they change. Birth abnormalities and cancer are two of the most severe medical diseases that can result from issues that arise throughout this procedure. Understanding how cells develop normally will help us comprehend and possibly rectify the mistakes that result in various medical problems.
The creation of tissues and cells for medicinal treatments is another possible use for stem cells. Nowadays, damaged or ruined organs and tissues are frequently replaced with donated ones. Unfortunately, there are many more patients in need of transplants than there are available organs. In order to cure a variety of illnesses, disorders, and impairments such Parkinson’s disease, amyotrophic lateral sclerosis, spinal cord injury, burns, heart disease, diabetes, and arthritis, pluripotent stem cells may provide a regenerative supply of replacement cells and tissues.
Blood-forming stem cells
These are mainly found in peripheral blood, cord blood, bone marrow, etc. They are blood-forming cells that entirely renew and heal the injured tissue or organ.
Mechanosensitive Stem Cells
The umbilical cord, placenta, amniotic fluid, peripheral blood, and even deciduous teeth contain the majority of these substances. They have a strong capacity for proliferation, which makes them often employed in gene therapy.
Stem cells can be obtained from a variety of tissues, including adipose, liver, lung, and fetal tissue, as well as the placenta, amniotic fluid, peripheral blood, and even deciduous teeth. They have a strong capacity for proliferation, which makes them often employed in gene therapy.
- Endocrine Stem Cells
- Cord blood stem cells
- Grownup stem cells
- Endocrine Stem Cells
The umbilical cord, placenta, amniotic fluid, peripheral blood, and even deciduous teeth contain the majority of these substances. They have a strong capacity for proliferation, which makes them often employed in gene therapy.
Originating from blastocysts
- Best and most primitive source
- There are several moral and legal issues.
- Potential for some undesirable side effects including cancers Cord blood stem cells
- freely accessible source
- Abundance of stem cells
- Reduction in the risk of viral infection
- Effortless collection
- 100% greater donor-patient matches
- Extremely prolific
- GvHD risk and severity are reduced in HLA-matched and mismatched recipients.
- Do not cause graft versus host reactions since they have not yet produced ABO and HLA antigens.
grownup stem cells - Most frequently used transplants are bone marrow
- Cancer patients receive bone marrow transplants to battle the disease.
- Less desirable than umbilical cord because they could contain latent viruses
- Population of MSC is small.
- Age-related significant decline in proliferative potential Blood Stream Stem Cells are harvested using cell
- Separators and ‘apheresis’
- Typically (autologous) for cell usage
- Low cell yield and a protracted process.
- Less plastic, which makes homing and engraftment a challenge.
- Mature tissue
- Skin, cornea, fat, teeth, small intestine, liver, and teeth can all be used to harvest stem cells.
- Gaining acceptance
- Can be altered genetically
- Utilized typically for Self (autologous)
- How do stem cells operate?
To replicate and grow into the appropriate tissue or to move to an injured location, stem cells can divide and renew themselves at will.
Stem cells have plasticity, or the capacity to differentiate into entirely distinct tissues.
Homing, or being drawn to the sight of hurt
Ability to engraft, or join with other tissue
advantages of stem cells
not harmful
without negative consequences
low cost of treatment
Prolong life expectancy Potential to treat numerous diseases
Treatable Conditions
Vascular Conditions
persistent heart failure
Myocardial Infarction Acute
Cardiomyopathy
The illness Buerger’s
Vascular Disease of the Periphery
disease of the liver
Hepatic cirrhosis
disease of the cartilage and bones
Osteoarthritis
fractures that don’t heal
Neuromuscular Conditions
spinal palsy
Several Sclerosis
Alzheimer’s disease
Spinal Cord Damage
Stroke
Alzheimer’s condition
muscle weakness
muscle atrophy in the spine
Autism ALS
Haematological Conditions
Chronic Leukemias
persistent leukemias
Disorders of Myelogenesis
Marrow Illness
Thallasemia
Disorders of Myeloproliferation
Diseases of Lymphoproliferation
Immune system diseases that are inherited
Problems with Plasma Cells
Additional cancers
Cancer, diabetes, anti-aging, eye disorders, and other diseases are all somewhat curable by stem cell therapy.
