Marfan Syndrome Treatment In India

Connective tissue, which is made up of fibers that support and anchor your organs and other body structures, is affected by the genetic illness known as Marfan syndrome. The most frequently impacted organs in Marfan syndrome are the skeleton, eyes, blood vessels, heart, and eyes. In order to lessen the strain on your aorta, Marfan Syndrome Treatment in India typically involves taking drugs to maintain a low blood pressure. Monitoring the development of damage on a frequent basis is crucial. Many Marfan syndrome sufferers eventually need aortic repair surgery. When compared to other industrialized countries, India’s cost of Marfan Syndrome treatment is affordable. The success may be partially attributed to the skill of the oncologists and surgeons as well as the state-of-the-art medical equipment used in the best Indian hospitals. In addition to these advantages, India is very well-liked because of its low costs without lowering clinical standards.

A condition of the connective tissues called Marfan syndrome. Your body is held together by connective tissue, which also supports a number of different structures. In Marfan syndrome, the connective tissue is abnormal. Your eyes, skin, lungs, bones, tendons, cartilage, and blood vessels are all impacted as a result. Patients with Marfan syndrome tend to be tall and skinny, with eerily long arms, legs, fingers, and toes. Damage from Marfan syndrome can range from minor to severe. It can be fatal if your aorta, a big blood vessel that connects your heart to the rest of your body, is injured.

The indications and symptoms of Marfan syndrome can differ widely, even within members of the same family, due to the disorder’s propensity to impact so many distinct bodily regions. While some individuals only experience minor side effects, others experience potentially catastrophic consequences.

Marfan syndrome symptoms can include:

Since connective tissue is impacted by Marfan syndrome, your skeletal system, heart and blood vessels, eyes, skin, and organs may all be affected:

If you think you or your child may have Marfan syndrome, speak with your physician or pediatrician. The likelihood is that you will be referred to a specialist for additional evaluation if your doctor senses a problem.

A mutation in the gene that codes for the construction of fibrillin and elastic fibers, both significant constituents of connective tissue, results in Marfan syndrome. The name of this gene is fibrillin-1 (FBN1).

Typically, Marfan syndrome is inherited. The pattern is “autosomal dominant,” which means it can only be inherited from one parent who also has Marfan syndrome and that it affects both men and women equally. Patients with Marfan syndrome have a 50% probability of passing the condition on to their offspring.

In 25% of cases, an unexplained etiology results in a new gene deficiency. The fact that not everyone with Marfan syndrome experiences the same symptoms and that some people’s symptoms are more severe than others gives rise to the term “variable expression” genetic condition.

Birth is when Marfan syndrome first shows up. It’s possible that you won’t get a diagnosis until you’re a teen or young adult.

A team of medical professionals may be needed to confirm the diagnosis and create a treatment strategy for Marfan syndrome because it can affect tissue all over your body. Before anything else, they will collect your medical history, perform a physical examination to check for common Marfan syndrome signs or discoveries, quiz you about your symptoms, and find out if any members of your family have experienced health issues that might be connected to Marfan syndrome.

To assess alterations in the heart, blood vessels, and issues with cardiac rhythm or to formally diagnose Marfan’s syndrome, the following tests may be used:

These consist of:
MRI, CT, and transesophageal echocardiography

The Marfan syndrome can be diagnosed with the help of a blood test. The FBN1 gene, which causes the majority of cases of Marfan syndrome, is the focus of this genetic test.